Claude Opus 4.5 vs Qwen 3.5 397B
Side-by-side benchmark comparison across coding, math, reasoning, speed, and pricing.
Claude Opus 4.5 by Anthropic wins on 10 of 15 benchmarks against Qwen 3.5 397B by Qwen, which leads on 5. This head-to-head comparison covers coding, math, reasoning, speed, and pricing metrics from our benchmark data.
Category-by-Category Breakdown
General Intelligence: In general intelligence, Claude Opus 4.5 scores 1468 on Chatbot Arena ELO compared to Qwen 3.5 397B's 1350, while Claude Opus 4.5 scores 89.5% on MMLU-Pro compared to Qwen 3.5 397B's 81.0%.
Coding: In coding, Claude Opus 4.5 scores 92.0% on HumanEval+ compared to Qwen 3.5 397B's 88.0%, while Claude Opus 4.5 scores 80.9% on SWE-bench Verified compared to Qwen 3.5 397B's 76.4%, while Claude Opus 4.5 scores 70.0% on LiveCodeBench compared to Qwen 3.5 397B's 54.0%.
Math: In math, Claude Opus 4.5 scores 90.0% on MATH compared to Qwen 3.5 397B's 87.0%, while Claude Opus 4.5 scores 96.5% on GSM8K compared to Qwen 3.5 397B's 95.0%.
Reasoning: In reasoning, Claude Opus 4.5 scores 87.0% on GPQA Diamond compared to Qwen 3.5 397B's 62.0%, while Claude Opus 4.5 scores 57.0% on ARC-AGI compared to Qwen 3.5 397B's 45.0%.
Context: In context, Qwen 3.5 397B scores 262K on Context Length compared to Claude Opus 4.5's 200K.
Pricing Comparison
Claude Opus 4.5 costs $5.0/1M input tokens and $25.0/1M output tokens, while Qwen 3.5 397B costs $0.55/1M input and $3.5/1M output. Qwen 3.5 397B is the more affordable option for API usage.
Speed Comparison
Claude Opus 4.5 generates output at 50 tok/s compared to Qwen 3.5 397B's 45 tok/s, and the time to first token is 1700 ms for Claude Opus 4.5 versus 600 ms for Qwen 3.5 397B. Claude Opus 4.5 delivers faster throughput.
Verdict
For developers prioritizing coding and general intelligence and math and speed, Claude Opus 4.5 has the edge. For those who value affordability, Qwen 3.5 397B is the stronger choice.
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Claude Opus 4.5 vs Qwen 3.5 397B — FAQ
Which is better, Claude Opus 4.5 or Qwen 3.5 397B?
Claude Opus 4.5 wins on more benchmarks overall (10 vs 5). However, the best choice depends on your specific needs — each model excels in different areas.
How does Claude Opus 4.5 compare to Qwen 3.5 397B for coding?
Claude Opus 4.5 is better for coding, scoring 80.9% on SWE-bench Verified compared to 76.4%. SWE-bench tests real-world software engineering by resolving actual GitHub issues.
Is Claude Opus 4.5 cheaper than Qwen 3.5 397B?
Yes, Qwen 3.5 397B is cheaper. Claude Opus 4.5 costs $5.0/1M input and $25.0/1M output tokens. Qwen 3.5 397B costs $0.55/1M input and $3.5/1M output tokens.
Which is faster, Claude Opus 4.5 or Qwen 3.5 397B?
Claude Opus 4.5 is faster, generating output at 50 tok/s compared to 45 tok/s. Faster output speed means shorter wait times for API responses.
What benchmarks does the Claude Opus 4.5 vs Qwen 3.5 397B comparison cover?
This comparison covers 15 benchmarks including Chatbot Arena ELO, MMLU-Pro, HumanEval+, MATH, GPQA Diamond, SWE-bench Verified, Output Speed, LiveCodeBench, and more. Metrics span general intelligence, coding, math, reasoning, speed, and cost categories.